Toolkit/System

Features/Improvements

Base Software
  • End of Windows 10 support.
  • Docker Desktop: ZEN 3.14 will automatically start/stop Docker Desktop with ZEN to enable smooth operation.
  • Container Applications: The following applications require the installation of Docker Desktop and the respective container which are available from the ZEISS Microscopy Installer:
    • Axioscan Spatial Biology (Tissue Detection, Co-Registration).
    • Lattice Light Sheet (Lattice Lightsheet LED Reflex Correction).
    • ZEN Toolkit AI (ZEN Toolkit AI: Intellesis Denoising).
    • AI Sample Finder (AI Sample Finder).
  • Compatibility of instance segmentation models: To use older instance segmentation models trained on arivis Cloud before 21st October 2025 with the latest NVIDIA graphics cards (Blackwell architecture), retrain the affected models on arivis Cloud to generate a models compatible with latest NVIDIA GPUs. Models trained after this date require NVIDIA GPUs with CUDA Compute Capability ≥ 7.0. On systems with older, incompatible NVIDIA GPUs, you must disable GPU usage in ZEN to run these newer models (in Tools > Options > arivis Cloud deactivate Enable NVIDIA GPU for Instance Segmentation). This forces CPU-based processing, so that these newer models can still be used on systems with older NVIDIA hardware.

AI Toolkit
  • New AI Denoising based on container technology.
  • Integrated CAREamics library (Jug Group at Human Technopole).
  • Advanced AI denoising features: cohesive denoising result for z-stacks with new 3D denoising, N2V2 to remove checkerboard artifacts, Struct2N to remove correlated noise.
  • Full integration in image processing, direct processing, live denoising and OAD scripting environment.

Lightfield 4D
  • Support for Lightfield 4D on LSM900 and 980.

Microscopy Copilot
  • Introduction of wide-field microscopes.
  • Improved answer content and form through agentic AI.
  • Instrument-aware answers: Copilot will provide answers relevant to the available instrument and software.
  • Now also available through a web browser.

ZEN Early Access Features
  • Workflows: Test an upcoming workflows feature allowing users to create and manage workflows for automation and smart microscopy.

Axioscan 7
  • Optimized prescan of transparent samples: faster, high contrast, works with standard sample detection.
  • Improved Scan Profile Editor: better color scheme, clearer user interface structure, simpler sample detection method selection.
  • Improved focus defaults for coarse focusing.
  • Improved management of scan profiles.
  • Clean user interface for magazine view and Axioscan tool.
  • Offers arivis Hub.
  • New hardware: Axiocam 820m.

Axiocam 7xx/8xx
  • New CMOS pixel correction algorithm.